Heather L. Handl: search on Z-Library

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1

Hitting multiple targets with multimeric ligands

Handl, Heather L, Vagner, Josef, Han, Haiyong, Mash, Eugene, Hruby, Victor J, Gillies, Robert J

Journal:

Expert Opinion on Therapeutic Targets

Year:

2004

Language:

english

File:

PDF, 533 KB

english, 2004

2

Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors

Josef Vagner, Liping Xu, Heather L. Handl, Jatinder S. Josan, David L. Morse, Eugene A. Mash, Robert J. Gillies, Victor J. Hruby

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

3

Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors

Josef Vagner, Liping Xu, Heather L. Handl, Jatinder S. Josan, David L. Morse, Eugene A. Mash, Robert J. Gillies, Victor J. Hruby

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 423 KB

english, 2008

4

Design, Synthesis, and Biological Evaluation of Achiral Analogues of Duocarmycin SA (I).

Kristen Daniell, Michelle Stewart, Erik Madsen, Minh Le, Heather Handl, Natalie Brooks, Konstantinos Kiakos, John A. Hartley, Moses Lee

Journal:

Year:

2005

File:

PDF, 12 KB

2005

5

A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties

Stanley Kupchinsky, Sara Centioni, Tiffany Howard, John Trzupek, Shane Roller, Virginia Carnahan, Heather Townes, Bethany Purnell, Carly Price, Heather Handl, Kaitlin Summerville, Kimberly Johnson, Ja

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 678 KB

english, 2004

6

Development of a lanthanide-based assay for detection of receptor–ligand interactions at the δ-opioid receptor

Heather L. Handl, Josef Vagner, Henry I. Yamamura, Victor J. Hruby, Robert J. Gillies

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

7

Sequence specific recognition of DNA by tailor-made hairpin conjugates of achiral seco-cyclopropaneindoline-2-benzofurancarboxamide and pyrrole–imidazole polyamides

Carly A. Price, Brian M. Lingerfelt, Heather L. Handl, Konstantinos Kiakos, John A. Hartley, Moses Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 319 KB

english, 2005

8

Design, synthesis, and validation of rigid linkers for bioactive peptides

Yasunari Monguchi, Josef Vagner, Heather L. Handl, Umasish Jana, Lucinda J. Begay, Victor J. Hruby, Robert J. Gillies, Eugene A. Mash

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 167 KB

english, 2005

9

Novel furano analogues of duocarmycin C1 and C2: design, synthesis, and biological evaluation of seco-iso-Cyclopropylfurano[2,3-e]indoline (seco-iso-CFI) and seco-Cyclopropyltetrahydrofurano[2,3-f]quinoline (seco-CFQ) analogues

Tiffany T. Howard, Brian M. Lingerfelt, Bethany L. Purnell, Adrienne E. Scott, Carly A. Price, Heather M. Townes, LuAnne McNulty, Heather L. Handl, Kaitlin Summerville, Stephen J. Hudson, J.Phillip Bo

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 343 KB

english, 2002

10

Solid-Phase Synthesis of Heterobivalent Ligands Targeted to Melanocortin and Cholecystokinin Receptors

Jatinder S. Josan, Josef Vagner, Heather L. Handl, Rajesh Sankaranarayanan, Robert J. Gillies, Victor J. Hruby

Journal:

International Journal of Peptide Research and Therapeutics

Year:

2008

Language:

english

File:

PDF, 317 KB

english, 2008

11

Lanthanide-based time-resolved fluorescence of in cyto ligand–receptor interactions

Heather L Handl, Josef Vagner, Henry I Yamamura, Victor J Hruby, Robert J Gillies

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 429 KB

english, 2004

12

Novel targeting strategy based on multimeric ligands for drug delivery and molecular imaging: homooligomers of α-MSH

Josef Vagner, Heather L. Handl, Robert J. Gillies, Victor J. Hruby

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 169 KB

english, 2004

13

Design, synthesis, and biological evaluation of achiral analogs of duocarmycin SA

Kristen Daniell, Michelle Stewart, Erik Madsen, Minh Le, Heather Handl, Natalie Brooks, Konstantinos Kiakos, John A. Hartley, Moses Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 306 KB

english, 2005

14

Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides

James L Toth, Carly A Price, Erik C Madsen, Heather L Handl, Stephen J Hudson, Richard B Hubbard, III, J.Phillip Bowen, Konstantinos Kiakos, John A Hartley, Moses Lee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 148 KB

english, 2002

15

Lanthanide-based luminescent assays for ligand-receptor interactions

Heather L. Handl, Robert J. Gillies

Journal:

Year:

2005

Language:

english

File:

PDF, 142 KB

english, 2005

16

Rigid Linkers for Bioactive Peptides

Vagner, Josef, Handl, Heather L., Monguchi, Yasunari, Jana, Umasish, Begay, Lucinda J., Mash, Eugene A., Hruby, Victor J., Gillies, Robert J.

Journal:

Bioconjugate Chemistry

Year:

2006

Language:

english

File:

PDF, 216 KB

english, 2006

17

Cell-Specific Targeting by Heterobivalent Ligands

Josan, Jatinder S., Handl, Heather L., Sankaranarayanan, Rajesh, Xu, Liping, Lynch, Ronald M., Vagner, Josef, Mash, Eugene A., Hruby, Victor J., Gillies, Robert J.

Journal:

Bioconjugate Chemistry

Year:

2011

Language:

english

File:

PDF, 4.26 MB

english, 2011

18

Synthesis and Evaluation of Bivalent NDP-α-MSH(7) Peptide Ligands for Binding to the Human Melanocortin Receptor 4 (hMC4R)

Handl, Heather L., Sankaranarayanan, Rajesh, Josan, Jatinder S., Vagner, Josef, Mash, Eugene A., Gillies, Robert J., Hruby, Victor J.

Journal:

Bioconjugate Chemistry

Year:

2007

Language:

english

File:

PDF, 500 KB

english, 2007

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